Cholinergic and adrenergic effects of tityustoxin.
نویسندگان
چکیده
The effects of purified scorpion toxin (Tityustoxin or TsTX) were investigated on the isolated guinea-pig and rat ileum, rat spleen strip and hen rectal caecum. The contraction of the ileum was due only in part to the release of acetylcholine, whereas the contraction of the spleen strip and the relaxation of the rectal caecum were due to the release of catecholamines.
منابع مشابه
Effect of nitric oxide modulation on the basic and rate-dependent electrophysiological properties of AV-node in the isolated heart of rabbit: The role of adrenergic and cholinergic receptors
Introduction: Recent studies showed that nitrergic system have specific modulatory effects on electrophysiological properties of atrioventricular (AV) node. The aim of this study was to determine the effects of nitric oxide (NO) on the electrophysiological properties of isolated rabbit AV node and to investigate the role of adrenergic and cholinergic receptors in the mechanism of its action...
متن کاملPresence of prejunctional D2-dopaminoceptors and α2-adrenoceptors on the cholinergic nerve of the common bile duct of guinea pig
On most adrenergic and cholinergic nerve terminals, prejunctional α-adrenoceptors belonging to the α2-subtype have been identified. Activation of these receptors will decrease the release of norepinephrine. It has been reported that several isolated tissue preparations contain prejunctional dopamine receptors, the stimulation of which inhibits neurotransmission. It has remained uncertain whethe...
متن کاملThe Effect of Hydro alcoholic Extract of Aloe Vera (L.) Brum. F, on the Movement of Large Intestine of Male Rats and Its Interaction with Cholinergic, Adrenergic and Nitric Oxide System
Background and aim: Aloe vera leaves have long been used in medicine and nutrition used by various communities. Some of the physiological effects of this plant have been used to treat some gastrointestinal disorders such as gastric ulcer, gastric acid back to esophagus. Therefore, In the present study, the effect of hydroalcoholic extract of aloe vera on mechanical activity of isolated colon of...
متن کاملThe effect of hydro-alcoholic extract of Glycyrrhiza glabra on the cardiovascular system of male rats with normal blood pressure and its interaction with cholinergic and adrenergic systems
Introduction: Glycyrrhiza glabra (Licorice) has been traditionally used as a medicinal plant in Iran for treatment of diseases such as gastric ulcer and arthrosclerosis. In this study, in order to determine some of its mechanisms, effects of hydroalcoholic extract of Glycyrrhiza glabra was examined on the blood pressure in rats. Methods: Adult male rats were anesthetized via injection of pen...
متن کاملMechanical activity of isolated aorta strips after prolonged exposure to low frequency electromagnetic fields and its interaction with the cholinergic and adrenergic systems in male rat
Introduction: Public concern about the potential effects of electromagnetic field (EMF) on human health is increased by progressive usage of electrical devices in modern life. The aim of this study was to investigate the effect of prolonged exposure to low frequency EMF on the mechanical activity of isolated thoracic aorta strips in rats. Methods: Fourteen male rats were randomly allocated into...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- General pharmacology
دوره 7 2-3 شماره
صفحات -
تاریخ انتشار 1976